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Temporal trajectories of species A in network (A1). The trajectories were generated using (a) the SSA, (b) the MSMC method, and (c) the HyMSMC method. The parameters are k1 = k-1 = 100 s-1 and k2 = k-2 = 0.01 s-1 and the initial state is XA(t = 0) = 1500, XB(t = 0) = Xc(t = 0) = 0.
