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Impaired erythropoiesis in Pim-1-, Pim-2-, and Akt-1-deficient animals
| Genotype | CFU-Es |
|---|---|
| WT | 355 ± 28 |
| Pim-1KO | 154 ± 24 |
| Pim-2KO | 113 ± 11 |
| Pim-1KO/Pim-2KO | 105 ± 13 |
| Pim-1KO/Akt-1KO | 79 ± 11 |
| Pim-2KO/Akt-1KO | 53 ± 19 |
| Pim-1KO/Pim-2KO/Akt-1KO | 18 ± 8 |
Mean ± SD of erythroid colony-forming units (CFU-Es) (n = 3) observed after the differentiation of bone marrow cells from mice of each genotype.
See Table 1 for abbreviations.
