Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of GATA-1 and GATA-3 effects on gene expression in T cells
|
Induction of Th2 genes
|
Suppression of Th1 genes
|
|||||||
|---|---|---|---|---|---|---|---|---|
| IL-4 | IL-5 | IL-13 | CCR4 | CRTH2 | IFNγ | CXCR3 | CCR5 | |
| GATA-3 | ++++ | ++++ | +++ | +++ | +++++ | + | +/- | +/- |
| GATA-1 | ++ | +++ | ++ | ++ | ++++ | +++ | ++++ | ++++ |
Each + represents a 20% change in T-cell subsets expressing the indicated protein as monitored by flow cytometry compared with HDV-expressing T cells.
