Table 5.

Allogeneic T-cell proliferation in the presence of MVA-TRICOM–infected CLL cells

Patient, stimulator cells	Allogeneic proliferation stimulation index
1
Uninfected	1.0
MVA-WT	1.3
MVA-TRICOM	131.0
2
Uninfected	0.6
MVA-WT	0.7
MVA-TRICOM	121.8
4
Uninfected	0.6
MVA-WT	0.8
MVA-TRICOM	68.6
16
Uninfected	11.7
MVA-WT	9.4
MVA-TRICOM	34.4
17
Uninfected	2.9
MVA-WT	2.9
MVA-TRICOM	179.6
18
Uninfected	9.0
MVA-WT	3.1
MVA-TRICOM	35.8

CD3⁺ T cells from healthy donors were stimulated with uninfected, MVA-WT– or MVA-TRICOM–infected CLL cells, at a ratio of stimulator to effector cells equal to 1:10. Proliferation was measured as ³H-thymidine incorporation on day 5 of culture. Stimulation index was calculated as cpm (T cells + CLL cells)/cpm (T cells alone).