Table 5.
Isolation and characterization of aerolysin-resistant T-cell clones from patients with PNH
| Patient no./colony no. | Colony type | Exon | Codon | Position and mutations | Consequence |
|---|---|---|---|---|---|
| 5/1 | T-cell/AE | 3 | 247 | 826insTA | frame shift |
| 5/2 | T-cell/AE | 3 | 247 | 826insTA | frame shift |
| 5/3 | T-cell/AE | 3 | 247 | 826insTA | frame shift |
| 5/4 | T-cell/AE | 3 | 247 | 826insTA | frame shift |
| 6/1 | T-cell/AE | 5 | 335 | 1089G>A | Gly→Glu |
| 6/2 | T-cell/AE | 5 | 335 | 1089G>A | Gly→Glu |
| 6/3 | T-cell/AE | 5 | 335 | 1089G>A | Gly→Glu |
| 6/4 | T-cell/AE | 5 | 335 | 1089G>A | Gly→Glu |