Table 3.
Treatment response in evaluable patients according to baseline platelet counts
SUMMIT
|
CREST*
|
||
---|---|---|---|
BPC less than 75 × 109/L | BPC 75 × 109/L or greater | BPC 75 × 109/L or greater | |
No. patients | 35 | 157 | 26 |
CR, no. (%) | 3 (9) | 15 (10) | 1 (4) |
PR, no. (%) | 8 (23) | 26 (17) | 9 (35) |
MR, no. (%) | 2 (6) | 12 (8) | 3 (12) |
Overall response (CR, PR, MR), no. (%) | 13 (37) | 53 (34) | 13 (50) |
BPC indicates baseline platelet count; CR, complete response; PR, partial response; and MR, minor response.
No patient in CREST receiving bortezomib 1.3 mg/m2 had a baseline platelet count less than 75 × 109/L.