Table 2.
Conditional bcl-x−/− | Bled control | Unbled control | |
---|---|---|---|
Spleen | |||
Total TER-119+ cells | 294 ± 56 | 16 ± 0.8† | 2.4 ± 0.4† |
Apoptotic TER-119+ cells | 34 ± 8.9 | 0.9 ± 0.2† | 0.1 ± 0.04† |
Marrow | |||
Total TER-119+ cells | 4.2 ± 0.8 | 10 ± 1.0† | 6.8 ± 1.1 |
Apoptotic TER-119+ cells | 0.2 ± 0.08 | 0.2 ± 0.01 | 0.1 ± 0.05 |
Total body* | |||
Total TER-119+ cells | 299 ± 57 | 27 ± 1.1† | 9 ± 1.4† |
Apoptotic TER-119+ cells | 34 ± 8.9 | 1.1 ± 0.2† | 0.2 ± 0.05† |
Erythroid progenitors are shown as × 10−7. All data are mean ± SEM of 6 mice.
Total body equals the sum of cells in the spleen and marrow.
P < .05 using t test comparing to conditional bcl-x−/−.