Table 5.

Odds ratios and 95% confidence intervals for the association between common IL10 haplotypes in distal and proximal promoter region and all non-Hodgkin lymphoma (NHL), and B-cell, T-cell, diffuse large B-cell lymphoma, and follicular lymphoma among non-Hispanic whites

		All NHL			B-cell lymphoma			T-cell lymphoma			Diffuse large B-cell lymphoma			Follicular lymphoma
Haplotype*	Controls, %‡	%‡	Odds ratio†(95% CI)	P	%‡	Odds ratio†(95% CI)	P	%‡	Odds ratio†(95% CI)	P	%‡	Odds ratio†(95% CI)	P	%‡	Odds ratio†(95% CI)	P
T-A-C-C	32.4	27.3	1.0	—	25.8	1.0	—	34.8	1.0	—	24.3	1.0	—	24.1	1.0	—
A-G-C-C	33.0	38.8	1.44 (1.15-1.80)	.002	39.3	1.54 (1.21-1.96)	< .001	36.8	1.04 (0.56-1.92)	.90	40.7	1.67 (1.19-2.34)	.003	39.4	1.70 (1.15-2.50)	.007
T-A-T-A	22.4	23.5	1.28 (1.00-1.64)	.05	24.0	1.37 (1.05-1.79)	.02	19.6	0.86 (0.43-1.73)	.68	25.0	1.54 (1.06-2.23)	.023	27.4	1.73 (1.14-2.63)	.011
T-G-C-C	10.4	8.8	1.01 (0.73-1.40)	.95	9.1	1.10 (0.78-1.57)	.58	8.8	0.81 (0.32-2.00)	.64	9.7	1.25 (0.77-2.01)	.37	6.2	0.83 (0.44-1.56)	.57
Global test†	—	—	—	.029	—	—	.01	—	—	.97	—	—	.043	—	—	.017

Pvalues of less than .05 are italicized.

— indicates not applicable.

^*Order of SNPs comprising the IL10 haplotypes: -3575T>A, -1082A>G, -819C>T, and -592C>A.

^†Odds ratios and global test are adjusted for age.

^‡Percentages may not add to 100% because of the presence of rare haplotypes not presented in this table.