Table 3.
Prevalence of comorbidities among 708 patients included in the training set with cumulative incidences and multivariate HRs of comorbidities for 2-year NRM
| Comorbidity | Prevalence, % | 2-year NRM, % | Multivariate HR* |
|---|---|---|---|
| Bleeding† | 1 | 0 | 0.0 |
| Headache† | 4 | 8 | 0.3 |
| Osteoarthritis† | 1 | 11 | 0.4 |
| Gastrointestinal disease | 9 | 20 | 0.5 |
| Coagulopathy | 6 | 30 | 0.6 |
| Osteoporosis† | 1 | 75 | 0.7 |
| Renal, mild‡ | 10 | 24 | 0.8 |
| Endocrine disease | 5 | 31 | 1.0 |
| Asthma† | 2 | 14 | 1.1 |
| Pulmonary, mild‡ | 16 | 18 | 1.1 |
| Hypertension | 10 | 33 | 1.2 |
| Arrhythmia | 5 | 35 | 1.3 |
| Cardiac‡ | 5 | 37 | 1.3 |
| Inflammatory bowel disease | 1 | 31 | 1.3 |
| Diabetes | 3 | 50 | 1.6 |
| Cerebrovascular disease | < 1 | 67 | 1.6 |
| Psychiatric disturbance† | 9 | 29 | 1.8 |
| Hepatic, mild‡ | 16 | 30 | 1.9 |
| Obesity† | 2 | 33 | 1.9 |
| Infection† | 4 | 40 | 1.9 |
| Rheumatologic | 4 | 45 | 2.3 |
| Peptic ulcer | 1 | 38 | 2.5 |
| Renal, moderate/severe‡ | 2 | 42 | 2.6 |
| Pulmonary, moderate‡ | 24 | 36 | 3.0 |
| Prior solid tumor‡ | 2 | 38 | 3.1 |
| Heart valve disease | 2 | 33 | 3.3 |
| Pulmonary, severe‡ | 9 | 39 | 3.7 |
| Hepatic, moderate/severe‡ | 4 | 43 | 3.9 |
| Peripheral vascular disease | 0 | — | — |
— indicates not applicable.
*
Adjusted for all other comorbidities, age, high disease risk, and conditioning type.
†
Newly investigated comorbidities.
‡
Comorbidities with modified definitions compared with the original CCI.