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. 2005 Jul 14;106(9):3271–3284. doi: 10.1182/blood-2005-01-0150

Table 4.

Summary of mtDNA heterogeneity in single CD34+ cells, T cells, B cells, and granulocytes

Heterogeneity
Poly-C tract
Cell type Assay, no.* Total rate,% (no.) Unique, % (no.) Substitution, % (no.) np 303-315, % (no.)
CD34+ cells 456 37.9 ± 3.6 (173) 13.4 ± 2.2 (61) 14.7 ± 5.7 (67) 22.3 ± 9.3 (101)
T cells 456 36.4 ± 14.1 (164) 18.6 ± 7.9 (84) 15.2 ± 9.0 (69) 21.5 ± 15.4 (96)
B cells 442 36.0 ± 10.7 (160) 16.5 ± 2.5 (73) 15.4 ± 6.7 (69) 19.7 ± 13.4 (87)
Granulocytes 376 47.7 ± 7.4 (178) 35.4 ± 4.1 (132) 32.3 ± 2.4 (121) 13.7 ± 10.2 (50)

Np indicates nucleotide position.

*

All assays were from donor no. 5

Statistically significant difference (P < .05) from granulocytes