Table 1.
Total fetal liver hematopoietic progenitors
Genotype | CFU-MIX, × 105 | BFU-E, × 103 | CFU-E, × 105 | CFU-GM, × 105 | CFU-MEG, × 103 |
---|---|---|---|---|---|
WT | 1.23 ± 0.003 | 47 ± 0.27 | 4.0 ± 0.005 | 2.5 ± 0.002 | 6.1 ± 0.03 |
p85β+/- | 1.37 ± 0.002 | 41 ± 0.18 | 4.2 ± 0.003 | 3.0 ± 0.005 | 6.8 ± 0.05 |
p85α-/- | 0.6 ± 0.005 | 20 ± 0.1* | 3.0 ± 0.001* | 1.5 ± 0.001* | 3.66 ± 0.06* |
p85α-/-; p85β+/- | 0.1 ± 0.001*† | 2.8 ± 0.15*† | 1.1 ± 0.001*† | 0.21 ± 0.001*† | 0.7 ± 0.04*† |
Data are presented as the mean plus or minus the standard error of the mean.
P < .02 compared with WT
P < .05 compared with p85α-/-