Table 1.

Percentage of GFP⁺ cells in mice that were given transplants of marrow cells expanded in response to F36VFGFR1 or F36VMpl signaling

			F36VFGFR1 with helper		F36VMpl with helper
Cell type	F36VFGFR1 without helper, 15 d after BMT	F36VMpl without helper, 15 d after BMT	15 d after BMT	36 d after BMT	15 d after BMT	36 d after BMT
RBCs	31.4 (4.3)	11.1 (5.2)	11.2 (2.8)	5.7 (1.2)	1.8 (0.3)	0.9 (0.1)
Platelets	20.1 (4.7)	20.1 (10.7)	2.5 (0.3)	0.1 (0.04)	0.37 (0.1)	0.02 (0.02)
Granulocytes	94.8 (1.9)	88.4 (10.9)	83.3 (3.1)	4.3 (2.4)	15.5 (5.0)	0.1 (0.09)
B cells	30.5 (7.6)	14.5 (14.8)	11.7 (3.8)	0.2 (0.1)	0.6 (0.2)	0.09 (0.02)
T cells	2.7 (1.05)	65.6 (9.9)	2.3 (1.4)	1.4 (1.0)	43.5 (12.5)	0.08 (0.04)
Monocytes	91.4 (3.1)	69.2 (26.6)	80.3 (7.1)	1.1 (0.6)	2.3 (0.5)	0.1 (0.09)

After 28 days of ex vivo culture in the presence of AP20187, 8 × 10⁶ cells containing either F36VFGFR1 or F36VMpl were transplanted into lethally irradiated mice, which were in turn evaluated on days 15 and 36 after transplantation. Without helper indicates 8 × 10⁶ ex vivo—expanded cells transplanted alone, without fresh marrow cells; with helper, ex vivo—expanded cells transplanted in combination with 1 × 10⁵ fresh marrow cells. All values are mean percentages of GFP⁺ cells (SD).