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Summary of model-based pharmacokinetic parameters
| Pharmacokinetic parameter | Estimate | Intersubject % CV |
|---|---|---|
| CL/F, L/h/70 kg | 148 | 23.7 |
| Vc/F, L/70 kg | 1 420 | 38.4 |
| Q2/F, L/h/70 kg | 694 | Not estimated |
| Vp/F, L/70 kg | 10 800 | Not estimated |
| MRT, d | 3.5 | 14.6 |
| t1/2 abs, h | 1.24 | 141 |
| Tlag, min | 13.4 | 11.8 |
Note that Tmax was observed at a mean ± SD of 1.96 ± 1.59 hours with a range of 0.25 to 8.02 hours.
