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. 2006 May 30;108(6):1895–1902. doi: 10.1182/blood-2005-11-012336

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Copyright © 2006, The American Society of Hematology

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Figure 4. — Anti-CR1/tPA loading does not damage carrier RBCs. ⁵¹Cr-labeled RBCs obtained from TgN-hCR1 mice, either naive (▵ and ) or loaded with anti-CR1/tPA in vitro (closed symbols), were injected into naive TgN-hCR1 mice. The blood level (inset) was determined at indicated times. The animals were humanely killed 1 hour after injection and the amount of ⁵¹Cr in the organs was measured (n = 5).

Inline graphic — Anti-CR1/tPA loading does not damage carrier RBCs. ⁵¹Cr-labeled RBCs obtained from TgN-hCR1 mice, either naive (▵ and ) or loaded with anti-CR1/tPA in vitro (closed symbols), were injected into naive TgN-hCR1 mice. The blood level (inset) was determined at indicated times. The animals were humanely killed 1 hour after injection and the amount of ⁵¹Cr in the organs was measured (n = 5).