Table 4.
Parasites and eggs detected in S mansoni–infected wild-type and eosinophil lineage–ablated mice
|
Worms
|
||||||
|---|---|---|---|---|---|---|
| Mouse strain | Males* | Females* | Pairs | Total | Eggs/g liver tissue, × 10-3 | Eggs in liver tissue, % |
| BALB/c | 2.1 ± 0.9 | 0 | 4.8 ± 0.4 | 11.7 ± 0.8 | 22.0 ± 1.4 | 83 ± 3 |
| ΔdblGATA | 1.4 ± 0.5 | 0 | 4.3 ± 0.5 | 9.9 ± 1.1 | 23.5 ± 2.6 | 81 ± 3 |
| C57BL/6 | 5.6 ± 1.0† | 0 | 5.6 ± 0.53 | 17.2 ± 1.0† | 16.7 ± 2.0 | 90 ± 2 |
| TgPHIL | 5.3 ± 1.5‡ | 0.4 ± 0.2 | 7.1 ± 1.3 | 19.6 ± 2.5‡ | 21.2 ± 3.0 | 92 ± 0.7 |
Analysis based on measurements taken at week 12 after exposure to cercariae of S mansoni as described in “Materials and methods.” Data are presented as plus or minus standard error of the mean.
Males and females refer to worms detected as singles.
P < .001 versus BALB/c.
P < .005 versus ΔdblGATA.