Table 5.
Characteristics of clonal repertoire in studied patients
| Diagnosis | No. clones per patient | Average clone, % | SEM | Expansion factor | Detection rate, % |
|---|---|---|---|---|---|
| AA | 2.32 | 6.75 ± 4.59 | 0.54 | 2.72 | 81 |
| MDS | 3.11 | 8.68 ± 7.6 | 0.71 | 3.42 | 97 |
| RA and RARS | 3.11 | 9.54 ± 9.34 | 1.22 | 3.46 | 100 |
| RAEB and RAEB-t | 3.11 | 7.78 ± 5.71 | 0.68 | 3.09 | 94 |
| PNH | 3.95 | 8.45 ± 9.47 | 1.04 | 3.26 | 95 |
| Hypoplastic BM* | 2.62 | 7.09 ± 5.17 | 0.49 | 2.78 | 84 |
| Hyperplastic BM | 3.04 | 9.50 ± 8.79 | 1.03 | 3.54 | 96 |
Expansion factor indicates the average fold expansion of VB families above the greater-than-2 SD values derived from healthy controls
SEM indicates standard error of mean; AA, aplastic anemia; MDS, myelodysplastic syndrome; RA, refractory anemia; RARS, refractory anemia with ring sideroblasts; RAEB, refractory anemia with excess of blasts; RAEB-t, RAEB in transformation; PNH, paroxysmal nocturnal hemoglobinuria; and BM, bone marrow
*
Includes AA and MDS