Skip to main content
. 2006 Jun 8;108(8):2726–2735. doi: 10.1182/blood-2006-02-001594

Table 1.

Summary of MDS-like/AML in SALL4B transgenic mice

Mouse ID Sex Founder Age, mo Phenotype Outcome and organs involved by AML*
464 M 464 19 MDS-like Died of MDS
4 M 464 22 MDS-like Alive
504 M 504 19 MDS-like Killed due to MDS
86 F 504 18 AML Killed; AML in BM, PB, liver, spleen, LNs
87 F 504 8 AML Killed; AML in BM, PB, liver, spleen, LNs
506 M 506 19 MDS-like Killed due to MDS
1336 F 506 14 AML Killed; AML in BM, liver, spleen, LNs
2548 F 506 14 AML Killed; AML in BM, liver, spleen
507 F 507 24 AML Died; AML in BM, PB, liver, spleen, LNs
23 M 507 22 MDS-like Killed due to MDS
25 M 507 8 AML Killed; AML in BM, PB, liver, spleen, LNs
26 M 507 14 MDS Killed due to MDS
27 M 507 22 MDS-like Alive
3058 F 507 12 AML Died; AML in BM, PB, liver, spleen and LNs
509 F 509 18 AML Killed; AML in BM, PB, liver, spleen, LNs, lung
510 F 510 24 MDS-like Killed due to MDS
*

Mice were killed when noticed to be ill. AML is defined to have more than 20% c-kit-positive immature cells in the bone marrow or peripheral blood, with leukemia cells involving multiple organs