Figure 2.

Ama1p is a Cdc20p family member. The predicted protein sequences for the AMA1 cDNA and other Cdc20 family members are presented. The arrows indicate the exon 1-exon 2 junction. Positions of predicted WD repeats are indicated by the solid triangles above the sequence. The black and gray shaded regions signify identical residues and conservative substitutions, respectively. The underlined sequence indicates additional amino acids identified by our sequence analysis that differ from the yeast genome project. Cdc20 family members representing human [55CDC (54)], Drosophila, [fzy2 (55)], and two from budding yeast [Hct1p/Chd1p (15, 16) and Cdc20p (56)] are presented.