Table 1.

SHIP-2 down-regulates FcγR-mediated phagocytosis in SHIP-1^−/− BMMs

	Phagocytic index, mean of 3 readings ± SD	P, compared with empty vector transfectants
Experiment 1
Vector	163.00 ± 20.66	—
WT-SHIP-2	122.33 ± 11.24	.018
D608A-SHIP-2	261.00 ± 16.09	.017
Experiment 2
Vector	247.67 ± 23.12	—
WT-SHIP-2	185.67 ± 8.74	.019
D608A-SHIP-2	355.33 ± 28.22	<.001
Experiment 3
Vector	202.00 ± 3.00	—
WT-SHIP-2	151.33 ± 3.75	.002
D608A-SHIP-2	299.00 ± 9.97	<.001

Three representative experiments are shown.

—indicates not applicable.