Table 2.
Binding of human-SIRPα and anti-CD47 to RBCs from multiple species
SIRPα1ex | BRIC126 | B6H12 | 2D3 | 6H9 | CIKm1 | mIAP301 | |
---|---|---|---|---|---|---|---|
Human | + | ++ | ++ | ++ | ++ | ++ | − |
Pig | ++ | + | − | − | ++ | ++ | ND |
Cow | −* | − | − | − | + | ++ | ND |
Rat | − | − | − | − | − | − | ND |
Mouse | − | ND | ND | ND | ND | ND | ++ |
+ indicates weak, >2×BKGD (background) and <10×BKGD; ++, strong, >10×BKGD; −, very weak, <2×BKGD; and ND, not determined.
Visibly distinct but very weak.