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. 2006 Jan 5;107(8):3378–3383. doi: 10.1182/blood-2005-07-2922

Table 1.

Patient characteristics dichotomized by immunoglobulin free light chain (FLC)

Percent of patients
Baseline characteristic All Baseline FLC < 152 mg/L Baseline FLC ≥ 152 mg/L P
Male 59 60 58 .79
Clonality, λ 74 75 72 .96
Prior therapy 36 43 29 .10
Kidney involvement 68 72 64 .40
Heart involvement 51 45 58 .17
Liver involvement 18 19 17 .97
Peripheral nerve involvement 17 18 15 .65
Autonomic nerve involvement 7 7 7 .98
Other organ involvement* 27 21 43 .034
Reduced conditioning intensity 24 15 32 .028
Year of PBSCT 1996-2002 41 43 39 .63

There were 60 patients with baseline FLC below 152 mg/L and 59 with baseline FLC at or above 152 mg/L. FLC indicates involved immunoglobulin free light chain.

*

Other includes 15 patients microvascular (claudication); 17 patients gastrointestinal; 3 patients pulmonary; 2 patients myopathy; and 1 patient factor X deficiency with splenic rupture. Total does not add up to 35 because patients had more than one type of involvement

Melphalan 100 mg/m2 to 140 mg/m2 without total body irradiation