Table 2.
Presenting clinical features of B-precursor patients enrolled on DFCI 95-01 with TEL/AML1 status at diagnosis
|
TEL/AML1 diagnostic status
|
|||
|---|---|---|---|
| Presenting feature | Negative, no. (%) | Positive, no. (%) | χ2P |
| Age | .05 | ||
| 0 y to less than 1 y | 10 (5) | 0 (0) | |
| 1 y to less than 10 y | 174 (78) | 69 (90) | |
| More than 10 y | 38 (17) | 8 (10) | |
| Sex | .65 | ||
| Male | 119 (54) | 39 (51) | |
| Female | 103 (46) | 38 (49) | |
| Risk | .23 | ||
| Standard | 127 (57) | 50 (65) | |
| High | 95 (43) | 27 (35) | |
| WBC count | .08 | ||
| Less than 50 × 109/L | 186 (84) | 58 (75) | |
| More than 50 × 109/L | 35 (16) | 19 (25) | |
| Unknown | 1 (0) | 0 (0) | |
| CNS disease | .57 | ||
| No | 179 (81) | 66 (86) | |
| Yes | 30 (14) | 7 (9) | |
| Traumatic | 10 (4) | 3 (4) | |
| Unknown | 3 (1) | 1 (1) | |
| Ethnicity | .75* | ||
| White | 179 (81) | 66 (86) | |
| Black | 10 (4) | 3 (4) | |
| Hispanic | 24 (11) | 7 (9) | |
| Other | 9 (4) | 1 (1) | |
| Asparaginase treatment | .14 | ||
| Randomized E coli | 59 (27) | 26 (34) | |
| Randomized Erwinia | 56 (25) | 24 (31) | |
| Assigned E coli | 107 (48) | 27 (35) | |
For TEL/AML1-negative patients, n = 222; for TEL/AML1-positive patients, n = 77.
*
Fisher exact test.