Table 1.
Hematopoietic parameters of Hoxb4 mutants and control littermates
| Cellularity
|
B-CFC
|
M-CFC
|
|||||
|---|---|---|---|---|---|---|---|
| BM, × 106 | Spleen, × 106 | Thymus, × 106 | BM, × 106 | Spleen, × 106 | BM, × 106 | Spleen, × 106 | |
| Hoxb4−/− | 29 ± 2.4 | 141 ± 74 | 97 ± 27 | 6.6 ± 2.4 | 0.4 ± 0.1 | 54 ± 2.4 | 3.8 ± 2.2 |
| Control | 25 ± 5.3 | 152 ± 18 | 86 ± 13 | 4.4 ± 0.8 | 0.4 ± 0.3 | 41 ± 14 | 2.9 ± 0.4 |
n = 3 mice for each group. Total cell numbers and numbers of B-cell and myeloid progenitors (B-cell and myeloid colony-forming cells, B-CFCs and M-CFCs, respectively) in BM, spleen, and thymus of Hoxb4−/− and control littermates.