Table 4.
The effect of 0157LPS on platelet counts in mice
| Strain | Median platelet counts without LPS, × 109/L*(range) | Median platelet counts with LPS, × 109/L (range) | P |
|---|---|---|---|
| C57BL/10ScSn | 950 (830-1080) | 140 (50-270)† | .001 |
| C57BL/10ScN | 700 (640-730) | 680 (600-720)‡ | — |
| C3H/HeN | 1121 (1065-1340) | 525 (495-550)§ | .001 |
| C3H/HeJ | 1100 (950-1270) | 1160 (980-1220)§ | — |
Intraperitoneal injection of mice with O157LPS reduced platelet counts in C57BL/10ScSN and C3H/HeN mice compared with mutated mice and with mice given injections of PBS.
—indicates not applicable.
n = 3 mice.
n = 9 mice.
n = 8 mice.
n = 6 mice.