Table 2.
Clinical features of patients according to the ZPI, FV Leiden and prothrombin polymorphisms
| No.(%) | Age at first episode, y (range) | Recurrence, no.(%) | Other risk factors, no.(%) | Familial history, no.(%) | |
|---|---|---|---|---|---|
| ZPI Lys25Arg | |||||
| Carrier | 723 (71.0) | 45 (33-58) | 203 (68.8) | 164 (22.7) | 138 (19.1) |
| Noncarrier | 295 (29.0) | 47 (33-60) | 77 (26.1) | 54 (18.3) | 39 (13.2)* |
| ZPI Ser40Gly | |||||
| Carrier | 259 (25.4) | 45 (33-56) | 70 (27.0) | 58 (22.4) | 38 (14.7) |
| Noncarrier | 759 (74.6) | 45 (33-59) | 210 (27.7) | 160 (21.0) | 139 (18.3) |
| ZPI Arg67Stop | |||||
| Carrier | 30 (2.9) | 49 (37-63) | 11 (36.7) | 9 (33.3) | 11 (40.0) |
| Noncarrier | 988 (97.1) | 45 (33-58) | 269 (27.2) | 209 (21.2) | 166 (16.8)† |
| ZPI Gly250Ser | |||||
| Carrier | 41 (4.0) | 49 (33-63) | 11 (29.3) | 10 (26.8) | 14 (36.6) |
| Noncarrier | 977 (96.0) | 45 (33-58) | 269 (27.5) | 208 (21.3) | 163 (16.7)† |
| FV Leiden | |||||
| Carrier | 145 (14.2) | 44 (30-56) | 42 (29.0) | 31 (21.4) | 30 (20.7) |
| Noncarrier | 873 (85.8) | 45 (33-59) | 238 (27.3) | 187 (21.4) | 147 (16.8) |
| PT 20210A | |||||
| Carrier | 101 (9.9) | 45 (32-56) | 22 (21.8) | 21 (20.8) | 16 (15.8) |
| Noncarrier | 917 (90.1) | 45 (33-59) | 258 (28.1) | 197 (21.5) | 161 (17.6) |
*
P < .05.
†
P < .005.