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. 2006 Mar 16;108(3):993–1000. doi: 10.1182/blood-2005-12-5148

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Figure 7. — Synergism between Nutlin-3a and F-ara-A is maintained in low Atm cases. Results of annexin V–binding assay in 30 Nutlin-sensitive samples (Figure 1) were separately analyzed with regard to Atm expression levels. Cells were incubated with the indicated concentrations of Nutlin-3a or F-ara-A, and the annexin V–positive fractions were measured by flow cytometry at 24 hours. Results are expressed as mean ± SEM. □ indicates Nutlin-3a; , F-ara-A; and ▪, combination.

Inline graphic — Synergism between Nutlin-3a and F-ara-A is maintained in low Atm cases. Results of annexin V–binding assay in 30 Nutlin-sensitive samples (Figure 1) were separately analyzed with regard to Atm expression levels. Cells were incubated with the indicated concentrations of Nutlin-3a or F-ara-A, and the annexin V–positive fractions were measured by flow cytometry at 24 hours. Results are expressed as mean ± SEM. □ indicates Nutlin-3a; , F-ara-A; and ▪, combination.