Table 2.
Correlation between CASP8AP2 gene expression and presenting clinicobiologic features
CASP8AP2 expression, no.
|
|||||
---|---|---|---|---|---|
Presenting feature | Patients studied, no. | Lower | Middle | Higher | P* |
Age | |||||
Younger than 1 y | 9 | 7 | 1 | 1 | .016 |
1 to 9 y | 203 | 58 | 71 | 74 | |
10 y or older | 76 | 31 | 24 | 21 | |
Race | |||||
White | 214 | 74 | 67 | 73 | .401 |
Black | 55 | 19 | 21 | 15 | |
Other | 19 | 3 | 8 | 8 | |
Sex | |||||
Male | 169 | 58 | 56 | 55 | .905 |
Female | 119 | 38 | 40 | 41 | |
WBC, × 109/L | |||||
Less than 10 | 90 | 27 | 30 | 33 | .328 |
10 to 50 | 85 | 27 | 26 | 32 | |
50 to 100 | 52 | 16 | 17 | 19 | |
More than 100 | 61 | 26 | 23 | 12 | |
BCR-ABL | |||||
Present | 16 | 6 | 5 | 5 | .936 |
Absent | 272 | 90 | 91 | 91 | |
TEL-AML1 | |||||
Present | 57 | 15 | 19 | 23 | .352 |
Absent | 231 | 81 | 77 | 73 | |
MLL-AF4 | |||||
Present | 18 | 10 | 5 | 3 | .099 |
Absent | 270 | 86 | 91 | 93 | |
Ploidy | |||||
Hyperdiploid† | 52 | 8 | 15 | 29 | < .001 |
Others | 236 | 88 | 81 | 67 | |
DNA index | |||||
1.16 or higher | 47 | 8 | 11 | 28 | < .001 |
Less than 1.16 | 241 | 88 | 85 | 68 |
WBC indicates white blood cell count.
Calculated by general association test.
More than 50 chromosomes.