Table 8.

Treatment with plasma in non-Stx–HUS patients with CFH and MCP mutations

Episode	CFH mutation, no.	MCP mutation, no.	IF mutation, no.	P
Treated episodes	57 (61)	23 (35)	6 (8)	< .001
Complete or partial remission	38 (57)	21 (23)	3 (6)	.023
No remission	19 (57)	2 (23)	3 (6)	.023
Nontreated episodes	4 (61)	12 (35)	2 (8)	< .001
Complete or partial remission	4 (4)	12 (12)	1 (2)	.001
No remission	0 (4)	0 (12)	1 (2)	.001

IF mutation group has not been included in statistical analysis. The numbers of patients for whom data were available are reported in parentheses. Plasma treatment includes infusion of 10 to 20 mL/kg/day and/or exchange of 1 to 2 plasma vol/day (or 30-40 mL/kg/day) for a total of 2 to 36 treatments in 2 days to 6 weeks.

P indicates CFH mutation versus MCP mutation. Significant P values are in italics.