Table 2.
Univariate analysis of correlates of HCV clearance
| Cleared HCV (%) | Chronic HCV | OR (95% CI) | P | |
|---|---|---|---|---|
| Age at infection (quartile) | ||||
| Younger than 2 y | 67 (40.1) | 100 | 1.00 | |
| 2 to 5 y | 41 (29.7) | 97 | 0.63 (0.39-1.02) | .059 |
| 6 to 15 y | 42 (26.1) | 119 | 0.53 (0.33-0.84) | .007 |
| 16 to 60 y | 23 (14.9) | 131 | 0.26 (0.15-0.45) | < .001 |
| Year of infection (quintile) | ||||
| 1947 to 1968 | 25 (18.2) | 112 | 1.00 | |
| 1969 to 1974 | 25 (21.6) | 91 | 1.23 (0.66-2.29) | .51 |
| 1975 to 1979 | 30 (27.0) | 81 | 1.66 (0.91-3.03) | .099 |
| 1980 to 1983 | 34 (28.8) | 84 | 1.81 (1.01-3.27) | .048 |
| 1984 to 1990 | 59 (42.8) | 79 | 3.35 (1.93-5.80) | < .001 |
| HBV coinfection | ||||
| HBV uninfected | 94 (28.7) | 234 | 1.00 | |
| Resolved HBV | 44 (24.3) | 137 | 0.80 (0.52-1.24) | .29 |
| Chronic HBV | 13 (59.1) | 9 | 3.60 (1.38-9.49) | .003 |
| Alcohol use* | ||||
| None | 106 (30.3) | 243 | 1.00 | |
| Less than 36 g/wk | 24 (27.3) | 64 | 0.86 (0.51-1.45) | .57 |
| 36 to 95 g/wk | 14 (16.3) | 72 | 0.45 (0.24-0.83) | .01 |
| 96 or more g/wk | 15 (18.8) | 65 | 0.53 (0.29-0.97) | .04 |
| Ancestry | ||||
| Non-African | 176 (28.0) | 452 | 1.00 | |
| African | 16 (19.0) | 68 | 0.60 (0.33-1.10) | .08 |
*
Alcohol use before knowledge of being infected with HCV. One drink was defined as 45 mL (1.5 oz) liquor, 120 mL (4 oz) wine, or 360 mL (12 oz beer) and was estimated to contain 12 g alcohol