Table 1.
Rheologic characteristics of venules and arterioles of WT and Tsp1-null mice
| Genotype mice and vessel type | Diameter, μm | Shear rate, s–1 |
|---|---|---|
| WT | ||
| Mesenteric venules | 172.3 ± 5.5 | 173.2 ± 22.6 |
| Caecum venules | 105 ± 32 | 337.3 ± 17.3 |
| Caecum arterioles | 52 ± 23* | 662.0 ± 87.2 |
| Tsp1-null | ||
| Mesenteric venules | 195.2 ± 6.1 | 168.5 ± 15.1 |
| Caecum venules | 109 ± 27 | 289.1 ± 21.3 |
| Caecum arterioles | 68 ± 16* | 652.5 ± 58.9 |
Values are mean ± SEM. The platelet count for WT mice was 666 ± 95 × 109/L and hematocrit was 32% ± 3%; for Tsp1-null mice, the platelet count was 664 ± 174 × 109/L and hematocrit was 33% ± 4%.
*
P = .01