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Time course of neutrophil infiltration. Neonatal WT, Mac-1 KO, and WT mice pretreated with CD11a-blocking antibody were injected intradermally with pathogenic anti-mBP180 IgG R530. Levels of infiltrating neutrophils at the IgG injection site were examined at the indicated time points after IgG injection. Data shown are the mean ± SEM. n = 6. *P < .05 and **P < .01 between R530-injected WT and Mac-1 KO mice.
