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Isotype switching is not disrupted in Stat3fl/flCD19Cre/+ mice. Stat3fl/flCD19Cre/+ (KO) mice (○) were able to elicit equivalent TD IgE responses (A) and TD IgA responses (B) compared with Stat3fl/flCD19+/+ (Wt) mice (•) in response to TD Ag. Mice were immunized with TNP-CGG as before, except that for induction of IgE, alum was used instead of CFA.
