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Receptor-ligand mismatch
| Father KIR | Corresponding ligand(s) in patient |
|---|---|
| 2DL1+ | HLA-CLys80 (Cw*04, Cw*05) |
| 2DL3+ | No cognate ligand in patient |
| 3DL1+ | HLA-Bw4 (B*53, B*44) |
Recipient HLA and donor KIR typing demonstrated the absence of HLA-CAsn80 ligand in the patient for KIR2DL3, which was present in the donor. This leads to a prediction of NK-cell alloreactivity by the KIR receptor-ligand model.
