. Author manuscript; available in PMC: 2007 Jun 22.

Published in final edited form as: J Biol Chem. 2006 Jun 22;281(34):24934–24944. doi: 10.1074/jbc.M604592200

Table 2.

Comparison of apo-hTF secondary structure to holo-pig TF and holo-chicken oTF.

	α -Helices
	N-lobe			C-lobe
Nomenclature	hTF^a	pTF^b	oTF^c	hTF	pTF	oTF
1	13–25	12–29	13–28	349–362	353–366	351–365
2	45–53	43–53	41–53	374–383	378–387	376–388
3	64–71	62–70	60–68	393–401	396–406	395–405
				418–420
4	109–111	108–110	105–109	441–443		444–448
5	129–135	127–134	121–136	461–466	463–478	460–476
5a	137–138	135–137		468–470
6	146–153	145–152	147–156	476–478	481–486	480–483
6a	168–170	166–169	167–174	502–504	499–501	496–499
6b	175–177
7	187–196	191–201	189–201	516–526	525–536	523–534
7a				537–540
8	210–213	212–217	211–217	549–551	545–550	543–549
8a	217–220	223–225	220–223		565–567
8a1				556–557
8b	235–240	239–244		572–576	580–585
9	260–273	263–278	259–275	594–608	600–617	600–616
10	311–315	314–319	315–321	647–651	655–659	652–658
11	317–328	321–331	321–332	653–662	661–673	658–669
12				669–677	677–682	674–686
	β -Stands
	N-lobe			C-lobe
Nomenclature	hTF^a	pTF^b	oTF^c	hTF	pTF	oTF
a	5–10	4–10	6–11	342–346	346–352	344–351
b	36–41	35–41	33–39	366–370	369–375	368–374
c	60–61	59–61	54–59	388–391	393–395	389–394
d	77–84	76–84	74–82	405–411	409–415	407–415
e	94–102	91–102	91–100	428–433	431–439	430–439
f	116–119	114–119	112–116	447–451	454–458	451–455
g	156–158	154–159	157–161	482–484	489–492	485–489
h	202–206	205–211	204–210	530–533	539–544	536–542
i	223–225	226–231	223–228	559–562	568–572	565–570
ia		235–238	232–234	568–570	575–579	574–576
j	244–247	247–259	244–255		588–591	586–597
ja	249–254			586–588	595–598
k	301–304	304–309	305–310	637–640	645–649	642–647

The apo-hTF secondary structural prediction was determined using PROCHECK (84)

From (27).

From (7). The N2- and C2-subdomains in each lobe are highlighted in aqua.