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Summary of the relative affinities of the wild type, shuffled and control interferons in the Daudi binding affinity assay
| Description | IC50, nM | SD | n | Fold over IFN-con1 |
|---|---|---|---|---|
| B9X14 | 0.04 | 0.01 | 13 | 96.6 |
| B9X25 | 0.44 | 0.09 | 6 | 9.05 |
| B9.1.2 | 2.04 | 0.61 | 5 | 1.95 |
| IFN-con1 | 3.97 | 1.19 | 15 | 1 |
| IFN-α2a | 4.62 | 0.82 | 11 | 0.86 |
| IFN-α8 | 7.45 | 0.57 | 3 | 0.53 |
| IFN-α1 | 1450 | 422 | 3 | 0.003 |
Fold improvements were calculated as a ratio of the mean IC50 (nM) values relative to IFN-con1
