Table 4.

Gel filtration results: Effect of ligand binding on IN oligomeric state

Sample	Mr, kDa	Oligomeric state	Elution volume, ml
IN	200	High-order oligomer	9.5, 12
IN + LEDGF 361–370	125	Tetramer	12.6
IN + LEDGF 402–411	125	Tetramer	12.6
IN + LTR DNA	65	Dimer	13.6
IN + DNA + LEDGF 361–370	130	Tetramer	12.8