Table 1.

Influence of galactose on antibody binding to FcRs

	Association constant (KA), M−1			A/I ratio
	FcγRIIB	FcγRIII	FcγRIV
6A6-IgG1	4.0 × 106*	5.0 × 105*	n.b.†	0.12 (III/IIB)*
6A6-IgG1 (G0)	2.6 × 106	9.1 × 105	n.b.†	0.35 (III/IIB)
6A6-IgG2b	3.9 × 106*	1.1 × 106*	2.9 × 107*	7.4 (IV/IIB)*
6A6-IgG2b (G0)	1.1 × 106	1.3 × 106	1.4 × 107	12.7 (IV/IIB)

*Association constants for untreated 6A6-IgG1 and -IgG2b as described previously (14).

^†No detectable binding.