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. 2007 Apr 24;8(4):R65. doi: 10.1186/gb-2007-8-4-r65

Table 1.

Some of the major transcripts from clustering analysis of the microarray data

Transcript Description
Cluster 1: highly enriched in sporocysts
 TC16551 Similar to 90 kDa heat shock protein
 TC13362 Homologue to 40S ribosomal protein S14
 TC16641 Homologue to elongation factor 1-alpha
 TC13505 Homologue to AUT1
 TC10547 Homologue to ribosomal protein S8
 TC17388 Similar to ribosomal protein S15a
 TC7475 Similar to 60S ribosomal protein L8
 TC11590 Ubiquitin/ribosomal fusion protein
 TC7403 Similar to 60S ribosomal protein L30
 TC9217 Weakly similar to cathepsin L-like cysteine proteinase
 TC17720 Similar to putative high mobility group-like nuclear protein 2
 TC11170 Similar to Usmg5 protein
Cluster 2: highly enriched in sporocysts and enriched in adults
 TC10486 Glutathione S-transferase 28 kDa (SM28 antigen)
 TC11169 Similar to Usmg5 protein
 TC13573 23 kDa integral membrane protein (SM23)
 TC7377 Similar to Y-box binding protein
 TC16738 14-3-3 protein homolog 1
 TC6863 Homologue to 14-3-3 protein homolog 1
 TC8189 Similar to dynein 8 kDa light chain flagellar outer arm
 TC13511 Homologue to AUT1
 TC13698 40S rRNA protein homolog
 TC16537 Heat shock 70 kDa homolog protein (HSP70) (major surface antigen
 TC10528 Probable dynein light chain (T-cell-stimulating antigen SM10)
 TC11430 Thioredoxin
 TC10691 Thioredoxin peroxidase
 TC16806 Similar to NADH dehydrogenase 6
 TC7615 Similar to ATP synthase lipid-binding protein-like protein
 TC11552 Homologue to cytochrome b
Cluster 3: highly enriched in sporocysts and enriched in cercariae
 TC13775 Antigen SM21.7
 TC13518 Homologue to NADH dehydrogenase subunit
 TC17477 Homologue to NADH dehydrogenase subunit 2
 TC17193 Similar to NADH dehydrogenase subunit 4
 TC13722 Homologue to NADH dehydrogenase subunit 5
 TC16807 Homologue to NADH dehydrogenase 6
 TC7310 Homologue to cytochrome c oxidase subunit 1
 TC14303 Homologue to ATPase subunit 6
 TC16782 Enolase
 TC16557 Myosin heavy chain - fluke
 TC10480 Elastase
 TC8910 Tubulin beta-2 chain.
 TC17016 Stathmin-like protein
 TC7850 Similar to actin-filament fragmenting protein
 TC7158 Similar to fibrillarin
Cluster 4: highly enriched in sporocysts and cercariae
 TC13565 Myosin light chain
 TC16878 Similar to glycerol-3-phosphate dehydrogenase [NAD+] cytoplasmic
 TC17004 Homologue to cytochrome c
 TC16870 ATP:guanidino kinase SMC74 (EC 2.7.3.-; ATP:guanidino phosphotransferase)
 TC17192 Homologue to NADH dehydrogenase subunit 4
Cluster 5: enriched in sporocysts and highly enriched in adults
 TC16575 Major egg antigen
 TC8654 Similar to anti-Mullerian hormone type II receptor precursor
 TC13882 Similar to 26S proteasome regulatory subunit
Cluster 6: highly enriched in adults
 TC10493 Cathepsin B1 isotype 1
 TC13457 Eggshell protein precursor
 TC13487 Homologue to eggshell protein precursor
 TC13492 Homologue to eggshell precursor protein
 TC8804 Weakly similar to retinoid X receptor RXR-2
 TC12198 Similar to mucin-like protein
 TC7011 Similar to putative retroelement
 TC16781 Extracellular superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1; EC-SOD)
 TC10637 Weakly similar to aquaporin 9 (small solute channel 1)
 TC9163 Similar to serine/threonine-protein kinase unc-51 (EC 2.7.1.-; (uncoordinated protein 5)
 TC7005 Similar to putative senescence-associated protein

Transcripts enriched in specific schistosome stages are organized into six major clusters. For an updated list of the latest version of TC sequences see Additional data file 8.