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Effect of SAP deficiency on survival of 129SV mice during bacterial infection. (a) E. coli O111:B4, 4.4 × 108 organisms injected i.v. (b) S. pyogenes H350, 2.1 × 105 organisms injected i.p. P values (log rank test) represent significant differences in survival between SAP−/− and SAP+/+ mice. Each result shown is typical of two to four identical experiments with each organism.
