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. 2000 Dec 19;97(26):14584–14589. doi: 10.1073/pnas.97.26.14584

Figure 2.

Figure 2

Effect of SAP deficiency on the survival of C57BL/6 mice during bacterial infection. (a) E. coli O111:B4, 108 organisms injected i.v. (b) E. coli J5, 109 organisms injected i.v. Each result shown in a and b is typical of at least two identical experiments with each organism. (c) E. coli J5, 109 organisms injected i.v. at time 0; isolated human SAP, 10 mg per mouse, was injected i.p. at −2 h and 16 h. P values (log rank test) represent significant differences in survival between SAP−/− and SAP+/+ or SAP-reconstituted SAP−/− mice.