FIGURE 1.

Cx40 G_j-V_j relationships under asymmetric normal to low [KCl] conditions. The steady-state G_j-V_j curves from six experiments under symmetrical control (A), asymmetric 75% trans [KCl] (B), asymmetric 50% trans [KCl] (C), and asymmetric 25% trans [KCl] conditions (D) are shown. The positive and negative V_j polarities of each curve were fit by Eq. 2 (thick solid line) and the results are presented in Table 1. Under asymmetric [KCl] conditions, the G_min and V_½ progressively increased on the low-[KCl] side while concomitantly decreasing on the high-[KCl] side.