TABLE 1.

V_j-dependent gating parameters for Cx40 gap junctions with low trans [KCl]

Parameter	Control −Vj* +Vj*		75% trans [KCl] −Vj* +Vj*		50% trans [KCl] −Vj* +Vj*		25% trans [KCl] −Vj* +Vj*
Gmax	1.0†	1.0†	1.0†	1.0†	1.0†	1.0†	1.33‡ ± 0.005	1.16‡ ± 0.003
Gmin	0.17 ± 0.001	0.19 ± 0.001	0.22 ± 0.002	0.09 ± 0.002	0.32 ± 0.002	0.06 ± 0.002	0.38 ± 0.002	0.03 ± 0.002
V½ (mV)	−49.7 ± 0.1	+49.2 ± 0.1	−59.0 ± 0.1	+47.0 ± 0.1	−61.3 ± 0.1	+37.9 ± 0.1	−66.8 ± 0.1	+30.0 ± 0.1
Valence (q)	3.71 ± 0.03	3.78 ± 0.03	3.41 ± 0.04	3.17 ± 0.04	3.23 ± 0.04	3.03 ± 0.04	2.74 ± 0.03	2.52 ± 0.03
Correlation coefficient (r)	0.96	0.96	0.95	0.92	0.96	0.91	0.97	0.93
N	6		6		6		6

^*V_j is defined relative to the 100% (140 mM) KCl-containing cell.

^†G_max was fixed to a value of 1.0 at V_j = 0 mV for the indicated curve fit.

^‡G_max was not fixed to a value of 1.0 at V_j = 0 mV for the indicated Boltzmann equation curve fits.