TABLE 2.

Symmetrical KCl V_j-dependent K_d values for spermine inhibition of Cx40 I_j

	Equilibrium dissociation constant, Kd (mM)
Vj (mV)	100% [KCl]	75% [KCl]	50% [KCl]	25% [KCl]
9.0 ± 0.1 (r)	9.46 ± 11.5 (0.87)	59.0 ± 21.1 (0.98)	16.0 ± 3.8 (0.98)	15.5 ± 3.2 (0.98)
13.8 ± 0.1 (r)	8.9 ± 6.2 (0.91)	11.1 ± 2.7 (0.97)	5.6 ± 0.9 (0.97)	5.9 ± 1.2 (0.97)
18.6 ± 0.1 (r)	5.3 ± 2.7 (0.91)	3.7 ± 0.3 (0.98)	2.1 ± 0.2 (0.97)	1.8 ± 0.2 (0.96)
23.5 ± 0.2 (r)	2.3 ± 0.5 (0.93)	1.8 ± 0.2 (0.96)	0.94 ± 0.13 (0.94)	0.76 ± 0.07 (0.95)
28.4 ± 0.2 (r)	1.2 ± 0.2 (0.91)	0.72 ± 0.08 (0.94)	0.47 ± 0.05 (0.93)	0.40 ± 0.03 (0.95)
33.4 ± 0.2 (r)	0.59 ± 0.19 (0.82)	0.40 ± 0.05 (0.92)	0.27 ± 0.03 (0.93)	0.22 ± 0.02 (0.94)
38.4 ± 0.2 (r)	0.27 ± 0.06 (0.85)	0.28 ± 0.03 (0.93)	0.18 ± 0.02 (0.93)	0.16 ± 0.01 (0.93)
43.5 ± 0.2 (r)	0.11 ± 0.03 (0.84)	0.22 ± 0.02 (0.93)	0.15 ± 0.01 (0.92)	0.13 ± 0.01 (0.93)
48.4 ± 0.2 (r)	0.094 ± 0.047 (0.75)	0.21 ± 0.02 (0.92)	0.16 ± 0.02 (0.90)	0.13 ± 0.01 (0.91)