Table 3. Summary of pmt-1 feeding-RNAi and chemical rescue phenotypes in C. elegans.
Starting worm (P0) | Added compound | Phenotype |
---|---|---|
L1 | None | P0 sterility |
5, 10 or 30 mM EA | P0 sterility | |
5 or 10 mM MME | Fertile adults | |
5 or 10 mM DME | Fertile adults | |
30 mM Choline | Fertile adults | |
Dauer | None | P0 sterility |
5, 10 or 30 mM EA | P0 sterility | |
5 or 10 mM MME | Fertile adults | |
5 or 10 mM DME | Fertile adults | |
30 mM Choline | Fertile adults | |
L4 | None | F1 L1/L2 or L3 arrest; lethality |
5, 10 or 30 mM EA | F1 L1/L2 or L3 arrest; lethality | |
5 or 10 mM MME | Wild-type F1 | |
5 or 10 mM DME | Wild-type F1 | |
30 mM Choline | Wild-type F1 |