Table 1.
Compounds | R | IC50, μMa |
---|---|---|
SAHA | 0.090 (± 0.004) | |
MS-275 | 3.2 (± 0.1) | |
1a | methyl | 134 (± 6) |
1b | ethyl | 449 (± 17) |
1c | n-propyl | 154 (± 7) |
1d | n-butyl | 72 (± 6) |
1e | allyl | 144 (± 9) |
1f | propargyl | 87 (± 5) |
1g | benzyl | 226 (± 11) |
Values are the means of three experiments with standard error given in parentheses.