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. 2000 Dec 19;97(26):14686–14691. doi: 10.1073/pnas.97.26.14686

Figure 2.

Figure 2

Time-course analysis of SVZ proliferation and progression of ridge migration. There is an initial proliferation of SVZ cells (arrowhead in a) in the first week of TGFα infusion into the caudate-putamen (CP) (a), followed by an en masse migration of the ridge into the striatum (arrowhead), starting at 9 days of TGFα infusion (b), progressing to the midstriatum by the 14th day (AC, anterior commissure) (c) *, Lateral ventricle. Septal infusions resulted in a medially directed EGFr-mRNA positive “septal” ridge (d, arrowhead a) originating in the medial SVZ adjacent to the striatum (d). Several other migration patterns can be seen, for example a colossal ridge (d, arrowhead b) or in the septum of the contralateral medial SVZ after striatal TGFα infusions (e).