Table 1.
Pharmacological Effects | Duration of Effects | |||
---|---|---|---|---|
1.0 mg/kg METH | 1.0 mg/kg AMP | |||
Males | Females | Males | Females | |
Distance Traveled | 118 ± 15 | 195 ± 43 | 141 ± 22 | 181 ± 25 |
Rearing Events | 118 ± 18 | 210 ± 27 | 144 ± 21 | 182 ± 25 |
Stereotypy | ND | ND | ND | ND |
3.0 mg/kg METH | 3.0 mg/kg AMP | |||
Males | Females | Males | Females | |
Distance Traveled | 226 ± 4 | 337 ± 52* | 239 ± 34 | 302 ± 42* |
Rearing Events | 222 ± 4 | 336 ± 46* | 239 ± 34 | 310 ± 39* |
Stereotypy | 218 ± 13 | 340 ± 52* | 240 ± 42 | 308 ± 32 * |
All data are shown as means ± SD.
P < 0.05 when compared to male values following the same treatment and dose. Data for METH effects (distance traveled and rearing) are from Milesi-Hallé et al., 2005. ND: Not determined, since stereotypies were only minimal or not detected after 1.0 mg/kg doses.