FIG. 1.

Predicted protein structure of C. neoformans deacetylases. The name of each protein is indicated to the right of the protein structure. Domains were identified by BLAST searches of the NCBI database (www.ncbi.nlm.nih.gov/structure/cdd/wrpsb.cgi). The N-terminal signal sequence and GPI anchor were determined. Domains are identified as follows: black rectangles, N-terminal signal sequence; white rectangles, polysaccharide deacetylase domain; omega, predicted GPI cleavage site. The dashed line above each protein indicates the extent of deletion in the corresponding genomic region for each deacetylase gene. aa, amino acids.