Table 1.
Histologic Features of Synchronous Breast Tumors.
| Cases | Type | Laterality | Tumor Size (cm) | Tumor Distance (cm) | Histologic Grade |
Estrogen Receptor | Progesterone Receptor | HER2 | |||
| Grade | T | P | M | ||||||||
| P1T1 | IDC (invasive micropapillary) | R | 1.3 | 1.3 | II | T2 | P3 | M1 | + | + | ND |
| P1T2 | IDC (NOS) | R | 0.8 | 1.3 | II | T2 | P3 | M1 | + | + | ND |
| P1T3 | IDC (NOS) | L | 0.7 | 0.75 | II | T3 | P2 | M1 | + | + | ND |
| P1T4 | IDC (NOS) | L | 0.7 | 0.75 | II | T3 | P2 | M1 | + | + | ND |
| P2T1 | IDC | L | 0.25 | ND | I | T1 | P2 | M1 | + | + | ND |
| P2T2 | IDC | L | 1.7 | ND | II | T2 | P2 | M1 | + | - | ND |
| P3T1 | IDC | L | 1.6 | ND | II | T3 | P2 | M1 | + | + | - |
| P3T2 | IDC | L | 2.0 | ND | II | T3 | P2–3 | M1 | + | + | - |
| P4T1 | IDC (tubular) | R | 0.8 | 0.4 | I | T1 | P2 | M1 | + | + | ND |
| P4T2 | IDC (tubular) | R | 1.6 | 0.4 | I | T1 | P2 | M1 | + | + | ND |
| P5T1 | IDC (NOS) | R | 2.3 | 1.8 | II | T2 | P2 | M3 | - | - | - |
| P5T2 | IDC (NOS) | R | 1.0 | 1.8 | II | T3 | P2 | M1 | - | - | - |
| P6T1 | IDC (NOS) | L | 2.7 | 3.0 | III | T3 | P3 | M3 | - | - | - |
| P6T2 | IDC (NOS) | L | 0.4 | 3.0 | I | T1 | P2 | M1 | + | - | - |
| P6T3 | IDC (NOS) | L | 0.5 | 1.7 | II | T3 | P2 | M1 | - | ||
| P7T1 | IDC (NOS) | L | 1.5 | 1.5 | II | T2 | P3 | M1 | + | + | - |
| P7T2 | IDC (NOS) | L | 1.1 | 1.5 | I | T1 | P3 | M1 | + | + | - |
| P8T1 | IDC (NOS) | R | 6.7 | 3.2 | III | T3 | P3 | M3 | - | - | - |
| P8T2 | IDC (NOS) | R | 2.5 | 3.2 | III | T3 | P3 | M3 | - | - | - |
| P9T1 | IDC | R | 1.5 | 5.0 | II | N2/3 | ND | ||||
| P9T2 | IDC | R | 1.0 | 5.0 | II | N2/3 | ND | ||||
| P10T1 | ND | ND | ND | ND | ND | ||||||
| P10T2 | ND | ND | ND | ND | ND | ND | |||||
Tumors are tabulated based on type, laterality, size, relative distance between synchronous tumors, histology, nuclear grading, and hormone receptor status (+, positive; -, negative). Histologic grade is composed of three parameters each scored 1–3: tubules, nuclear pleomorphism, and mitotic rate. Scores are added to give an overall grade (grade I = 3–5; grade II = 6 or 7; grade III = 8 or 9). Twenty-three samples from 10 patients were used for the study. From the 10 patient cases, 9 cases were unilateral synchronous tumors and 1 case was bilateral. All cases were invasive ductal carcinomas. ND = no data; NOS = not otherwise specified.