TABLE 2.

RISK OF LUNG CANCER DEVELOPMENT BASED ON THE DOSE OF INHALED CORTICOSTEROIDS

Triamcinalone Equivalents	Person-Years at Risk	Total (n = 10,474)	Lung Cancer (n = 423)	Unadjusted HR (95% CI)	Adjusted HR* (95% CI)
Continuous
Per 100 μg/d	33,436	10,474	423	0.98 (0.95–1.02)	0.96 (0.93–1.00)
Categorical
Nonusers	31,799	9,957	402	Referent	Referent
< 1,200 (μg/d)	928	298	16	1.36 (0.83–2.25)	1.13 (0.67–1.90)
⩾ 1,200 (μg/d)	709	219	5	0.56 (0.23–1.36)	0.39 (0.16–0.96)

Definition of abbreviations: CI = confidence interval; HR = hazard ratio; ICS = inhaled corticosteroids.

^*Adjusted for age, smoking status and smoking intensity, history of malignancy other than skin cancer, Seattle Index of Comorbidity score, and bronchodilator use.